Hi, I’m Andy. I like to tell stories with data.

01 Where I’ve Been

The thread of my interdisciplinary background is unlocking stories from large datasets that tell us something useful about the world.

1. Nov 2025 – Present · Remote
   Project Manager, Astera Institute
   Coordinating distributed scientific teams to advance structural biology and protein dynamics, bridging computational and experimental approaches to foster open, collaborative science across the US. Work products: Science in the Open, Structural Biology Landscape Directory
2. Apr 2025 – Nov 2025 · Hybrid
   Data Management Specialist, HHMI Janelia Research Campus
   Built data management strategies and open science initiatives, managed research platforms including Figshare and Protocols.io, and championed FAIR data principles across cross-functional teams. Work products: Citation Analysis Tool, Fly DISCO Showcase
3. Apr 2024 – Feb 2025
   Communications & Evaluations, NIH Common Fund
   Evaluated and communicated results of programs including Transformational CryoEM and MoTrPAC.
4. May 2023 – Apr 2024
   Postdoc, National Center for Biotechnology Information (NCBI)
   Bioinformatics of carbohydrate-binding enzymes to predict protein–glycan interactions.
5. Jul 2017 – May 2023
   PhD, Chemistry & Chemical Biology, Cornell University
   With Prof. Nozomi Ando. How essential enzymes respond to molecular signals.
6. Aug 2013 – May 2017
   BA, Chemistry, Bryn Mawr College

02 What I Do

03 Publications

1. Diribonuclease activity eliminates toxic diribonucleotide accumulation. Cell Rep 43, 114759 (2024). doi:10.1016/j.celrep.2024.114759
2. Conformational landscapes of a Class I ribonucleotide reductase complex during turnover reveal intrinsic dynamics and asymmetry. bioRxiv (2024). doi:10.1101/2024.06.16.599213
3. The three-sided right-handed β-helix is a versatile fold for glycan interactions. Glycobiology 34 (2024). doi:10.1093/glycob/cwae037
4. Conformational switching and flexibility in cobalamin-dependent methionine synthase studied by small-angle X-ray scattering and cryo-electron microscopy. Proc. Natl. Acad. Sci. USA 120, 2302531120 (2023). doi:10.1073/pnas.2302531120
5. Analysis of insertions and extensions in the functional evolution of the ribonucleotide reductase family. Protein Sci. 31 (2022). doi:10.1002/pro.4483
6. Comprehensive phylogenetic analysis of the ribonucleotide reductase family reveals an ancestral clade and the role of insertions and extensions in diversification. eLife (2022). doi:10.7554/eLife.79790
7. Convergent allostery in ribonucleotide reductase. Nat. Commun. 10, 1 (2019). doi:10.1038/s41467-019-10568-4

See everything on ORCID

04 Communication

Communications I have authored for a public audience. Scroll or use the arrows.

05 Projects worth a mention

An enzyme family tree

An editorial for my first, first-author paper. One of my first serious communications for a public audience, with a figure I built from our own protein models and the latest publicly available deep-learning model.

Read the digest

Every protein, every glycan

A major work in my postdoc: we analyzed every protein in the Protein Data Bank for its ability to bind glycans (carbohydrates), to help guide future protein–glycan studies. I am especially proud of the figures.

Read the paper

Mapping an enzyme’s evolution

A major result of my dissertation: we curated the largest dataset of ribonucleotide reductase sequences at the time to explore a new, previously unstudied subgroup.

Read the paper

Structural Biology Landscape Directory

A collection of public working notes that map the people, organizations, funding, software, and governance across scientific fields, starting with structural biology. Shared openly as one person’s attempt to make sense of a complex landscape.

Visit the site

Fly DISCO Showcase

A prototype showcase that links disparate datasets together to make research easier to explore and connect.

Visit the site

06 Skills & competencies